Creatine and Sarcopenia Disease

Creatine has been shown to increase strength and muscle mass in young adults in practically hundreds of studies at this point. Additionally, there was scant studies examining its effects on older individuals until more recently. The greatest threats to an aging adult’s abilities to stay healthy is the constant reduction of lean body weight (muscle groups and bones in particular) as they age. The clinical term for the loss of muscle is sarcopenia, and it’s going to get the respect it deserves by the healthcare and scientific community. For decades, that community has focused on the weakening of bones (osteoporosis) of aging adults but paid not enough attention to the loss of muscle mass which effects a man’s ability to be truly useful as they age just as much – if not more so, then a loss of bone mass.

What identifies sarcopenia from a medical perspective?

Sarcopenia can be defined as the age-related loss of muscle mass, strength and functionality. One thing is completely clear: it’s much easier, cheaper, and more results-oriented to prevent sarcopenia, or at minimum dramatically slow its progression, then it is to treat it later in life. Sarcopenia in most cases occurs after age of 40 and increases soon after the age of approximately 75. Although sarcopenia is commonly seen in physically inactive individuals, it is also frequently found in women and men who stay physically active throughout their lives. Therefore, it’s clear that even though physical activity is very important, physical inactivity is not actually the only contributing key to sarcopenia. Just like osteoporosis, sarcopenia is a multifactorial process that may normally include decreased hormone ranges (in particular, human growth hormone, IGF-1, and testosterone), a lack of necessary protein and calories in the diet, oxidative stress, inflamation related processes, as well as the decreasing activity of motor neurons.


Creatine and Older Adults

As a result of aging and inactivity, almost all atrophy an elderly individual’s muscle group is observed in the quick twitching fibers that happen to be recruited over the course of high-intensity, anaerobic actions (example, weight training, sprints, etc.). Surprisingly, these are absolutely the materials creatine has the essential unique effects on. One study labeled as “Creatine supplementation increases isometric energy and physical structure improvements utilizing strength exercise and training in more aged men and women” fed 28 healthy and well balanced women and men (just above sixty-five years old) either 5 grams everyday of creatine or placebo utilizing a unique, double blind method for fourteen weeks. Both of these testing groups were put on a resistance workouts (weight lifting) system for the duration of the research study. 14 weeks of resistance fitness exercises caused extensive improvements in all specifications of toughness and workable activities and muscular tissue fiber area for both social groups. Whatever, the people taking the creatine led to considerably greater improves in non-fat mass, higher improvement in isometric knee extension, much higher gains in isometric line and flexion strength, as well as a remarkable boost in intramuscular creatine amounts. The scientists came to the conclusion : “The addition of creatine supplementation to the workout routine stimulus improved the boost in total and non-fat mass, and gains in quite a lot of indices of isometric muscle potency.” A full slew of latest tests have been noticing equivalent effects on more aged individuals and coming to practically similar results.

An additional recent study named “Creatine supplementation gets better physical functionality in more aged men” by using a synonymous project as the above mentioned study noticed almost the same results. They concluded: “… information signals that seven days of creatine supplementation is effective at enhancing plenty of indices of muscle abilities, including workable clinical tests in elderly males with no negative side effects. Creatine supplements could be a very useful therapeutic approach for elderly adults to attenuate loss in muscle potency and functions of functional way of life activities.” Additional research came to synonymous results. However, it ought to be mentioned that not all tests have found this effect (Effects of creatine monohydrate intake in exercise-free and weight-trained more aged persons but they were much earlier studies that could have had some methodological imperfections. Irrespective, the bulk of the data, in specific the latest data, simply points to creatine as having great effects on energy and body structure in old persons, particularly when combined with a weight training exercise project. One very helpful present-day survey found the beneficial effects of creatine on energy and lean muscle mass in older grownups continued after they stopped using the creatine at least for the twelve weeks they tested these people. They concluded: “Withdrawal from creatine had no influence on the rate of energy, strength, and decrease of good muscle mass with 12 weeks of reduced-volume training program.” However, it’s the experience of most creatine consumers, and even most surveys in younger persons, that the excellent effects of creatine do in fact reduce in the long run if one ends utilizing creatine. Since there is no certain fact to go off creatine once established, the most useful results will most likely come from continued use.


Benefits оf Creatine Monohydrate – Important fоr High-Intensity Exercise Performance

Creatine monohydrate іѕ оnе оf thе mоѕt widely uѕеd forms оf creatine, а nitrogen-containing organic compound whісh іѕ naturally produced bу thе body. It іѕ а vеrу important substance bесаuѕе іt supplies thе body wіth thе energy іt nееdѕ bу increasing thе production оf adenosine triphosphate, thе substance thаt transports energy wіthіn thе cells needed fоr metabolism. In а pilot study conducted аmоng bоth young, healthy subjects аnd patients suffering frоm neuromuscular diseases, creatine monohydrate supplementation wаѕ shown tо hаvе increased body weight, hand grip, dorsiflexion, аnd knee extensor strength. If уоu аrе suffering frоm еіthеr Parkinson’s disease, multiple sclerosis, myasthenia gravis, Huntington’s disease оr thе Creutzfeldt-Jakob disease, creatine monohydrate mау bе аblе tо hеlр іn increasing уоur muscle strength аnd nervous control. Creatine supplementation іѕ popularly uѕеd tо enhance sports performance, аnd hаѕ bееn successfully tested іn thе treatment оf neuromuscular, neurological аnd atherosclerotic diseases. Creatine plays а key role іn brain energy stability bу acting аѕ buffer fоr adenosine triphosphate аnd іtѕ regulator, adenosine diphosphate. Anоthеr experiment conducted bу thе Macmaster University іn Hamilton, Ontario fоund thаt short term creatine monohydrate supplementation enhances high-intensity exercise performance іn bоth males аnd females. It wаѕ аlѕо shown thаt males thаt tооk whey protein supplements whіlе оn resistance training exhibited significant improvement іn knee extension peak torque аnd gained mоrе lean tissue mass thаn males engaged іn training alone. Males thаt tооk а combination оf whey protein аnd creatine monohydrate as Patt said from showed а muсh greater increase іn lean tissue mass аnd bench press thаn thоѕе whо supplemented wіth оnlу whey protein оr placebo.

More Creatine Exercise Studies

In аn experiment conducted bу thе University оf Sydney аmоng 45 young adults tо test hоw oral creatine supplementation wоuld enhance intelligence test scores аnd memory performance, thе results show thаt indeed, creatine supplementation hаѕ significant positive effect оn а person’s intelligence аnd memory. Thіѕ result сlеаrlу іndісаtеѕ thаt brain energy capacity plays а key role іn enhancing brain performance, intelligence аnd memory. Creatine plays а key role іn cellular energy metabolism аnd саn potentially play а role іn protein metabolism. Wіth regular supplementation оf creatine monohydrate, young healthy men аnd women mау experience а higher intensity exercise performance, increased skeletal muscle volume аnd phosphocreatine concentration, аnd increased fat free muscle mass. Rесеnt study аlѕо revealed thаt creatine monohydrate supplementation protects аgаіnѕt neuromuscular аѕ shown іn laboratory animal models оf Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, аnd аftеr ischemia. A lоw concentration оf phosphocreatine content hаѕ аlѕо bееn noticed іn skeletal muscles оf elderly patients аnd оf patients suffering frоm neuromuscular disorders.


Can creatine cause injury or muscle cramps

This is maybe by far the most well known creatine myth among the athletes. This is a post hoc fallacy and something that becomes repeated so much that people without having prior knowledge of creatine will most likely and unfortunately believe it to be reality. If an sportsperson who is using creatine gets a muscle cramp they’ll point the fingers at their own creatine utilize, while in fact the cramp is most probably as a direct consequence of deficit of water, improper electrolyte balance, or number of other causes that could possibly result in cramping.

In a new and very large (nearly 1500 participants) research, creatine supplementation did not lead to enhanced incidence of cramping amongst more athletes. In fact, the people taking creatine actually suffered from considerably less cramps than the non-creatine team. In a comparable vein, a lot of professional athletes mistakenly believe that creatine will improve their risk of harm. Nevertheless, study has demonstrated that creatine is unable to increase the possibility of injury.


The quantity of myths I just included are the most widespread you can find these days, although there are obviously more you will deal with if you look a little bit deeper. Hopefully I’ve suggested you to accept anything very negative you read about creatine monohydrate with a touch of suspicion from here on out. I recommend you to always try to find legitimate scientific materials when it comes to creatine or any other nutritional supplement. Don’t rely on the personal stories of good friends, fellow fitness enthusiasts, coaching staff, etc. Have confidence in published, peer-reviewed scientific tests. Be concered about any unrealistic claims you hear, whether they are negative or positive. While We’ve preferred to pay attention to debunking the negative myths related to creatine, the phrase of “buyers beware” obviously relates to the nutritional supplement business. Remember, creatine is not a steroid, so do not expect steroid-like effects, regardless of how lofty the manufacturer’s claims may be.


Lift Heavier with Creatine

If there’s one supplement that — since its introduction into the fitness world — has stood the test of time, it’s creatine monohydrate. Creatine is used by junior athletes, hobbyists, and professionals alike.

To date, over 500 peer-reviewed studies have examined the effects of creatine monohydrate, showing its beneficial effects on decreasing muscle recovery time, increasing non-aerobic endurance, and upping muscle gains. What’s more, it does so with minimal side effects.

What Is Creatine?

Creatine is a natural compound that’s made out of three amino acids: l-arginine, glycine, and theanine. Although many people wrongfully call it an anabolic steroid, it is nothing more than a combination of amino acids that are naturally found in the body. Your body is already using creatine right now!

Our bodies produce creatine in the liver or kidneys. However, they can also absorb and store the creatine found in protein-rich foods, such as meat, fish, and eggs.

The vast majority of the creatine in your body is stored in your muscles. During bouts of intense physical activity, your body delivers the creatine to assist with performing the movements (more on this below).

So, what is creatine monohydrate? Simply put, it is creatine with a water molecule attached to it. Because of its more stable composition, this is the type of creatine you’re most likely to find in supplement form. Micronized Creatine is another form of creatine that is ground into even smaller particles which makes for easier mixing and absorption.

How Does Creatine Work?

Without delving too deep into the (pretty complex) biochemistry of creatine, let’s break down exactly how this molecule works in the body.

If we remember anything from our high school science class, it’s that adenosine triphosphate (ATP) provides energy to your body’s cells. However, in order for your cell to use ATP, it has to break it down into several small molecules.

When ATP is broken down, several byproducts are produced. One such product is called adenosine di-phosphate (ADP) — which is ATP with one phosphate molecule missing.

On its own, ADP is essentially useless to the cell. However, when you add back the missing phosphate to the molecule, it can be converted into ATP and used by the cell again.

So, where does creatine come into play? Well, creatine donates its phosphate to ADP. As such, instead of having a bunch of useless molecules floating around, you create more ATP to charge your body’s physical activity.

That’s not all creatine does. In addition to increasing ATP production, creatine can increase water supply in muscle cells. The more hydrated your muscle cells, the greater the protein synthesis that allows your muscles to grow bigger and stronger.

As the cherry on top of the sundae, increasing muscle cell hydration means your muscles will look bigger. So, not only are you improving your performance, but looking great while doing so. An added bonus of building more muscle is increased testosterone. The more heavy compound lifts you do, the more your body will need to keep up and naturally produce more testosterone.

Is Creatine Safe?

Naturally, you may be wondering if supplementing with creatine is safe. Unlike many workout supplements, creatine has decades of research and hundreds of peer-reviewed studies to back up its safety.

As a molecule made of amino acids that is naturally produced by your body, creatine is very unlikely to pose any risks to your health. Studies support this, showing that supplementing with as much as 30 grams of creatine per day — over the course of decades — is not associated with any negative side effects.

Does Creatine Improve Athletic Performance?

Creatine can improve your athletic performance by increasing how much energy is available to your muscle cells. It is most effective with high-intensity exercise, such as those that require explosive movement.

Most notably, creatine is used by weightlifters to increase how much they can lift while cutting down on recovery time between sets. However, creatine can also enhance sprints, cycling, calisthenics, or any other movement that is focused on explosive power.

So, if you’re a long-distance marathon runner, does that mean that you should look the other way when you see a creatine supplement? Not so fast. Studies show that creatine can aid with muscle recovery, which can benefit athletes of any kind.

Boosting Your Athletic Performance With Muscle Boost

Creatine monohydrate is an effective supplement that can increase your energy during workouts, increase your muscle’s protein synthesis, and aid with muscle recovery.

Of course, to get the full benefits of this supplement, you want to go for the highest quality that you can find. For this, Muscle Boost has got your back. For a clean creatine supplement that has no fillers or additives, check out Muscle Boost — for your best performance yet.


Creatine for building strength

Creatine is a naturally occurring non-protein amino acid that is found in muscle tissue, most commonly in red meat like steak, and seafood like tuna and salmon. When consuming creatine-rich foods, your liver and kidneys take in the amino acids to make creatine, which is then transferred to your muscles as a form of cellular energy called creatine monohydrate. Creatine can also be consumed as a supplement, often in the form of Creatine Monohydrate.

Table of Contents

What is the Science Behind Creatine?

Creatine is a naturally occurring amino compound found in skeletal, cardiac, smooth muscle, and brain that plays an indispensable role in energy metabolism in almost all tissues. The body produces creatine from the amino acids methionine, glycine, and arginine (folate and vitamin B 12 are also catalysts), with most residing in skeletal muscle where about one-third exists as creatine and two-thirds as phosphocreatine.

The phosphorylated form, creatine phosphate, provides an immediate energy source for the brain and muscles, and therefore, the primary rationales for supplementation are to increase, rapidly replete, and prolong this energy source to increase the metabolic capacity of these target tissues, such as the capability of a muscle to contract more powerfully longer and heal faster.

How Does Creatine Affect Muscles?

It helps you recover between sets. This means a supplements’ value lies in boosting recovery speed, which in turn enhances the amount of work you’re able to do during a workout. Over time, this leads to faster gains in both strength and size. This supplementation can boost maximum power and performance in high-intensity anaerobic repetitive labor (work and rest periods) by 5 to 15%.

It has no significant effect on aerobic endurance, though it will increase power during short sessions of high-intensity aerobic exercise. An added bonus is high-intensity lifting and exercise can increase free testosterone in the body. This in combination with testosterone supplements is a recipe for gains and success.

Improved recovery leading to enhanced short and long-term gains: This supplementation may also work through other unique muscle-building mechanisms related to recovery, development, and muscular adaptations during the supplementing phase.

Does Creatine Help Prevent Injury and Aging?

Combined with weight training, It slows the loss of bone mass as you age and could ease the effects of osteoarthritis, where joints become stiff and painful. That said, creatine, inevitably, has different effects on individuals.

The effects of it should be evident in a week in most using the supplement— with your training volume and strength increasing. Muscle fibers grow quicker after this supplementation and resistance-based exercise, according to research published in the journal Medicine & Science in Sports & Exercise.

It may also participate in reducing certain types of muscle damage from high-intensity resistance training and endurance exercise allowing more complete recovery before subsequent exercise bouts.

Is It Safe to Use for Teenagers and Adults?

The goal of this supplementation is to deliver a greater and prolonged accrual of gains, as opposed to a non-supplemented state, that can translate to the “field of play” (specific sports activities) because continuous better workouts allow greater and continuous improved muscular adaptations.

Moreover, the safety of this supplementation is undisputed, and in fact, offers therapeutic and recovery benefits in otherwise healthy individuals of all ages.